Colorectal is a nasty form of cancer and one of the leading causes of death in the West.
Given the number of foreign substances that are found in our food supply, it seems important that we find as many easy and natural means of prevention as possible to add to our health toolboxes.
Garlic may already be on your list, but let’s see if there is any research that supports its use to help prevent colorectal cancer.
Researchers out of Japan sought to determine if garlic, aged garlic extract (AGE) to be exact, might have any effect on three different colorectal cancer cell lines in an in vitro setting.
Their results, published in March 2006 in The Journal of Nutrition, could give us some hope.
As mentioned previously, they studied three different colorectal cancer cell lines: HT29, SW480, and SW620.
When tested against AGE, AGE significantly suppressed proliferation of all three in the cell culture.
When it came to whether or not AGE could also suppress the invasive activity of these three cell lines, it was able to do so significantly in both the SW480 and SW620 lines, but interestingly enough not the HT29 cell line.
However, AGE exposure was shown to result in cell apoptosis (programmed cell death) in the HT29 cell line.
So, AGE was shown to inhibit each of the three colorectal cancer cell lines, but in different ways, which is very encouraging if looking for a one-stop-shop natural preventive agent.
Now, that is not to say that AGE is a one-stop-shop colorectal cancer preventer, but this research is very encouraging nonetheless.
Of course it must be noted that these experiments were done on cell cultures rather than in actual humans, so more research would be welcomed to determine how these results translate to real life. This will help us identify not only whether or not the results achieved are similar, but what dosages are appropriate to achieve them.
In the absence of that information, we can safely stow this away in our toolbox of potential natural means to help prevent yet another scourge of a disease.
So talk to your doctor or licensed healthcare provider if you are thinking of incorporating AGE into your dietary and/or supplement plan for your health, to make sure it is safe and appropriate for you in your circumstances. As always, this article is provided for informational purposes only and is not medical advice.
And for more information on what health potential garlic may have in store for us, click here.
Thanks and all the best to you on your pursuit of great!
Reference: https://jn.nutrition.org/article/S0022-3166(22)08157-3/fulltext#%20
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